neutral protamine Hagedorn insulin - PMC

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Select item 80950101.

(Ultra‐)long‐acting insulin analogues versus NPH insulin (human isophane insulin) for adults with type 2 diabetes mellitus

Cochrane Database Syst Rev. 2020; 2020(11): CD005613. Published online 2020 Nov 9. doi: 10.1002/14651858.CD005613.pub4

PMCID:: PMC8095010

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Severe Hypoglycemia Risk With Long-Acting Insulin Analogs vs Neutral Protamine Hagedorn Insulin

Marie C. Bradley, Yoganand Chillarige, Hana Lee, Xiyuan Wu, Shruti Parulekar, Stella Muthuri, Michael Wernecke, Thomas E. MaCurdy, Jeffrey A. Kelman, David J. Graham

JAMA Intern Med. 2021 May; 181(5): 598–607. Published online 2021 Mar 1. doi: 10.1001/jamainternmed.2020.9176

PMCID:: PMC7922234

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Select item 64861603.

Insulin for the treatment of women with gestational diabetes

Julie Brown, Luke Grzeskowiak, Kathryn Williamson, Michelle R Downie, Caroline A Crowther, Cochrane Pregnancy and Childbirth Group

Cochrane Database Syst Rev. 2017 Nov; 2017(11): CD012037. Published online 2017 Nov 5. doi: 10.1002/14651858.CD012037.pub2

PMCID:: PMC6486160

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Select item 80942204.

(Ultra‐)long‐acting insulin analogues for people with type 1 diabetes mellitus

Cochrane Database Syst Rev. 2021; 2021(3): CD013498. Published online 2021 Mar 4. doi: 10.1002/14651858.CD013498.pub2

PMCID:: PMC8094220

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Long-term efficacy and safety of insulin detemir compared to Neutral Protamine Hagedorn insulin in patients with Type 1 diabetes using a treat-to-target basal–bolus regimen with insulin aspart at meals: a 2-year, randomized, controlled trial

P C Bartley, M Bogoev, J Larsen, A Philotheou

Diabet Med. 2008 Apr 1; 25(4): 442–449. doi: 10.1111/j.1464-5491.2007.02407.x

PMCID:: PMC2327220

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Select item 61344326.

Association of Initiation of Basal Insulin Analogs vs Neutral Protamine Hagedorn Insulin With Hypoglycemia-Related Emergency Department Visits or Hospital Admissions and With Glycemic Control in Patients With Type 2 Diabetes

Kasia J. Lipska, Melissa M. Parker, Howard H. Moffet, Elbert S. Huang, Andrew J. Karter

JAMA. 2018 Jul 3; 320(1): 53–62. Published online 2018 Jun 23. doi: 10.1001/jama.2018.7993

PMCID:: PMC6134432

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Select item 64646097.

Different insulin types and regimens for pregnant women with pre‐existing diabetes

Sinéad M O'Neill, Louise C Kenny, Ali S Khashan, Helen M West, Rebecca MD Smyth, Patricia M Kearney, Cochrane Pregnancy and Childbirth Group

Cochrane Database Syst Rev. 2017 Feb; 2017(2): CD011880. Published online 2017 Feb 3. doi: 10.1002/14651858.CD011880.pub2

PMCID:: PMC6464609

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Select item 46351828.

Use of Insulin Lispro Protamine Suspension in Pregnancy

Annunziata Lapolla, Maria Grazia Dalfrà, Ester Romoli, Matteo Bonomo, Paolo Moghetti

Adv Ther. 2015; 32(10): 888–905. Published online 2015 Oct 26. doi: 10.1007/s12325-015-0244-y

PMCID:: PMC4635182

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Select item 80947549.

Drug treatments for managing cystic fibrosis‐related diabetes

Cochrane Database Syst Rev. 2020; 2020(10): CD004730. Published online 2020 Oct 19. doi: 10.1002/14651858.CD004730.pub5

PMCID:: PMC8094754

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Select item 512426110.

A randomised, open-labelstudy of insulin glargine or neutral protamine Hagedorn insulin in Chinese paediatric patients with type 1 diabetes mellitus

Min Liu, Zhiguang Zhou, Jinhua Yan, Pin Li, Wenhui Song, Junfen Fu, Xiaobo Chen, Weigang Zhao, Li Xi, Xiaoping Luo, Liang Sha, Xueyuan Deng, Chunxiu Gong

BMC Endocr Disord. 2016; 16: 67. Published online 2016 Nov 26. doi: 10.1186/s12902-016-0146-2

PMCID:: PMC5124261

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Select item 290104411.

An Analysis of the Mixing Efficiency of Neutral Protamine Hagedorn Cartridges

Scott V. Monte, Patrick Comerford, Jr., Natalie Dearing

J Diabetes Sci Technol. 2010 May; 4(3): 658–660. Published online 2010 May 1. doi: 10.1177/193229681000400321

PMCID:: PMC2901044

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Select item 367157612.

A RETROSPECTIVE STUDY COMPARING NEUTRAL PROTAMINE HAGEDORN INSULIN WITH GLARGINE AS BASAL THERAPY IN PREDNISONE-ASSOCIATED DIABETES MELLITUS IN HOSPITALIZED PATIENTS

Subarna M. Dhital, Yoram Shenker, Melissa Meredith, Dawn Belt Davis

Endocr Pract. Author manuscript; available in PMC 2013 Sep 1.

Published in final edited form as: Endocr Pract. 2012 Sep-Oct; 18(5): 712–719. doi: 10.4158/EP11371.OR

PMCID:: PMC3671576

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Select item 736634813.

The Evolution of Insulin and How it Informs Therapy and Treatment Choices

Irl B Hirsch, Rattan Juneja, John M Beals, Caryl J Antalis, Eugene E Wright, Jr.

Endocr Rev. 2020 Oct; 41(5): 733–755. Published online 2020 May 12. doi: 10.1210/endrev/bnaa015

PMCID:: PMC7366348

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Select item 298453914.

How pharmacokinetic and pharmacodynamic principles pave the way for optimal basal insulin therapy in type 2 diabetes

S Arnolds, B Kuglin, C Kapitza, T Heise

Int J Clin Pract. 2010 Sep; 64(10): 1415–1424. doi: 10.1111/j.1742-1241.2010.02470.x

PMCID:: PMC2984539

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Select item 958583415.

Maternal and neonatal outcomes with the use of long acting, compared to intermediate acting basal insulin (NPH) for managing diabetes during pregnancy: a systematic review and meta-analysis

Jijiao Wang, Xiaochen Ji, Ting Liu, Nan Zhao

Diabetol Metab Syndr. 2022; 14: 154. Published online 2022 Oct 21. doi: 10.1186/s13098-022-00925-7

PMCID:: PMC9585834

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Select item 894732516.

New Horizons: Next-Generation Insulin Analogues: Structural Principles and Clinical Goals

Mark A Jarosinski, Yen-Shan Chen, Nicolás Varas, Balamurugan Dhayalan, Deepak Chatterjee, Michael A Weiss

J Clin Endocrinol Metab. 2022 Apr; 107(4): 909–928. Published online 2021 Nov 24. doi: 10.1210/clinem/dgab849

PMCID:: PMC8947325

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Select item 825608017.

Assessment of Regular and NPH Insulin Concentration via Two Methods of Quantification: The Washington State Insulin Concentration Study (WICS)

Joshua J. Neumiller, Gang Chen, Cheyenne Newsome, Sally Hughes, Philip Lazarus, John R. White, Jr.

J Diabetes Sci Technol. 2021 Mar; 15(2): 324–328. Published online 2019 Oct 22. doi: 10.1177/1932296819883291

PMCID:: PMC8256080

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Select item 557391718.

Modeling Pharmacokinetic Profiles of Insulin Regimens to Enhance Understanding of Subcutaneous Insulin Regimens

Lai San Tham, Karen Schneck, Ali Ertekin, Jesus Reviriego

J Clin Pharmacol. 2017 Sep; 57(9): 1126–1137. Published online 2017 Apr 10. doi: 10.1002/jcph.899

PMCID:: PMC5573917

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Select item 725412719.

Comparing the efficacy and safety of insulin detemir versus neutral protamine hagedorn insulin in treatment of diabetes during pregnancy: a randomized, controlled study

Jing ji, Zhangya He, Zhao Yang, Yang Mi, Na Guo, Hong Zhao, Jiayi Gao, Zhengfeei Ma, Xiaoqin Luo, Zhen Han

BMJ Open Diabetes Res Care. 2020; 8(1): e001155. Published online 2020 Apr 6. doi: 10.1136/bmjdrc-2019-001155

PMCID:: PMC7254127

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Select item 290104320.

Assessment of the Mixing Efficiency of Neutral Protamine Hagedorn Cartridges

Pia Kaiser, Sebastian Maxeiner, Alexander Weise, Florain Nolden, Anja Borck, Thomas Forst, Andreas Pfützner

J Diabetes Sci Technol. 2010 May; 4(3): 652–657. Published online 2010 May 1. doi: 10.1177/193229681000400320

PMCID:: PMC2901043

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PMC Images search for neutral protamine Hagedorn insulin

Figure 1

Kaplan-Meier curve of follow-up 1 year persistence days between insulin glargine and neutral protamine Hagedorn insulin.

Real-world outcomes of US employees with type 2 diabetes mellitus treated with insulin glargine or neutral protamine Hagedorn insulin: a comparative retrospective database study

BMJ Open. 2013;3(4):e002348.
Figure 1Participant flow diagram.

ID, insulin detemir; NPH, Neutral Protamine Hagedorn insulin; QC, quality control.

Effects of Insulin Detemir and NPH Insulin on Body Weight and Appetite-Regulating Brain Regions in Human Type 1 Diabetes: A Randomized Controlled Trial

PLoS One. 2014;9(4):e94483.
Fig. 1

Sample selection and resulting patient counts. Non-mixed basal insulins are insulin detemir, insulin glargine, NPH (neutral protamine Hagedorn) insulin, and insulin degludec; T2DM was identified using ICD-10 codes E11.x and E14.x; T1DM was identified using ICD-10 codes E10.x, secondary diabetes as ICD-10 codes E08.x–E09.x, E13.x, and pregnancy as ICD–10 codes O00.x–O08.x, O10.x–O16.x, O20.x–O29.x, O30.x–O48.x, O60.x–O75.x, O80.x–O92.x, O94.x–O99.x, Z32.1, Z33.x–Z35.x, Z37.x, Z39.x

Basal Insulin Persistence, Associated Factors, and Outcomes After Treatment Initiation: A Retrospective Database Study Among People with Type 2 Diabetes Mellitus in Japan

Diabetes Ther. 2017 Feb;8(1):149-166.
Figure 1

Study protocol. BG, blood glucose; BMI, body mass index; OAD, oral antidiabetic drugs; NPH, Neutral Protamine Hagedorn insulin; PBTS, prandial bolus therapy with sulfonylurea; PPT, prandial premixed therapy; SU, sulfonylurea.

Comparison of thrice‐daily lispro 50/50 vs thrice‐daily lispro in combination with sulfonylurea as initial insulin therapy for type 2 diabetes

J Diabetes Investig. 2010 Aug 2;1(4):149-153.